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Our Team

The DMASC provides multi-disciplinary expertise in information technology, clinical research informatics, clinical trials auditing, clinical trials methodology and biostatistics, and operations management to support CP-CTNet activities.

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The DMASC is a collaboration between the University of Wisconsin School of Medicine and Public Health and Frontier Science Foundation
University of Wisconsin, School of Medicine and Public Health, Department of Biostatistics and Medical Informatics

The University of Wisconsin Data Coordinating Center (DCC) was established in 2016 as a component of the Clinical Trials Program in the Department of Biostatistics and Medical Informatics (BMI) in the UW School of Medicine and Public Health.

The DCC supports and is engaged in collaborative clinical research projects which are NIH- or industry-funded data coordinating centers.

The DCC plays a critical role in coordinating and implementing large multi-center randomized controlled trials (RCTs) and other types of clinical research studies, bringing expertise in planning, conduct, monitoring, analysis and reporting and in data management, quality control and quality assurance, and information technology support for trial monitoring and communication, all needed to complement the clinical investigators' content expertise.

Jens Eickhoff, PhD

Jens Eickhoff, PhD is the DMASC MPI and Director of the Administrative and Coordinating Unit. Dr. Eickhoff is a Distinguished Scientist in the Department of Biostatistics and Medical Informatics at the University of Wisconsin-Madison. He participates in advising the early phase cancer prevention clinical trial development at CP-CTNet Sites and works with CP-CTNet UG1 statisticians. In addition, he serves as an unblinded statistician for cross-network clinical trials and supports the data and safety monitoring board/committee responsible for CP-CTNet cross-network clinical trials. Dr. Eickhoff has been responsible for supporting the phase I cancer drug development program at the UW Carbone Cancer Center since 2004.

Frontier Science Foundation

Frontier Science Foundation has engaged in clinical trials collaboration and support for 50 years, providing accurate and cost-effective data management as well as statistical software development and maintenance for the collection and analysis of data to research networks, pharmaceutical companies, and investigators.

Frontier Science has participated in numerous multi-site, multi-trial networks including the AIDS Clinical Trials Group (ACTG), the Pediatric AIDS Clinical Trials Group and its successor, IMPAACT, the Eastern Cooperative Oncology Group (ECOG) and International Breast Cancer Study Group (IBCSG), the Pediatric HIV/AIDS Cohort Study (PHACS), the HIV/Cervical Cancer Prevention ‘CASCADE’ Clinical Trials Network ('CASCADE'), and TB-RePORT (Regional Prospective Observational Research in Tuberculosis) International (TBRI).

Frontier Science collaborates with scientists and technicians in more than 800 laboratories, universities, and medical centers around the world engaged in clinical trials and observational studies.

Sue Siminski, MS, MBA

Sue Siminski, MS, MBA is the DMASC MPI and Director of the Data Management and Reporting Unit. She has been working in clinical trials data management and related research activities for more than 30 years and currently serves as the Chief Executive Officer of Frontier Science Foundation.

The DMASC is composed of four operational units.

Data Management and Reporting Unit

Director: Sue Siminski

Leads: Kayla Denson, Kelly Dunn

Clinical Trials Auditing Unit

Director: Julie Chang

Lead: Holly Shaw

Administrative and Coordinating Unit

Director: Jens Eickhoff

Lead: Kelly Miller

Statistical Support Unit

Director: Guanhua Chen

Lead: Jen Zaborek

This project is supported by the National Cancer Institute (NCI) of the National Institutes of Health under award number UG1CA304955. The content is solely the responsibility of the authors and does not necessarily represent the official view of the National Institutes of Health.

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