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DMACC

The Data Management, Auditing, and Coordinating Center for the Cancer Prevention Clinical Trials Network (CP‑CTNet)
  • Data Management

  • Clinical Trial Auditing

  • Administration and Coordination

  • Data Management

  • Clinical Trial Auditing

  • Administration and Coordination

  • Data Management

  • Clinical Trial Auditing

  • Administration and Coordination

  • Data Management

  • Clinical Trial Auditing

  • Administration and Coordination

  • Data Management

  • Clinical Trial Auditing

  • Administration and Coordination

  • Data Management

  • Clinical Trial Auditing

  • Administration and Coordination

  • Data Management

  • Clinical Trial Auditing

  • Administration and Coordination

About CP-CTNet

The Cancer Prevention Clinical Trials Network (CP-CTNet) is a major program of the National Cancer Institute (NCI) Division of Cancer Prevention (DCP). The purpose of CP-CTNet is to perform and provide clinical trial support for the efficient conduct of early-phase clinical trials, evaluate the biologic effects of preventive agents and interventions, and determine clinically relevant correlates in order to advance their development for cancer prevention.

The key components of CP-CTNet are the CP-CTNet sites and the CP-CTNet Data Management, Auditing, and Coordinating Center (DMACC). Each CP-CTNet site consists of a Lead Academic Organization (LAO) and Affiliated Organizations (AOs) that work together to perform cancer prevention clinical trials.

About DMACC

The Data Management, Auditing and Coordinating Center supports the CP-CTNet sites and coordinates trans-network activities for centralized data management and reporting, clinical trials auditing, and administrative and logistical coordination across CP-CTNet sites. In addition, the DMACC collaborates with and advises the CP-CTNet sites with respect to trial design and protocol development.

The DMACC is led by KyungMann Kim, PhD, of the University of Wisconsin (as Principal Investigator) and Sue Siminski, MS, MBA, of Frontier Science Foundation (as sub-Principal Investigator).

What the DMACC Does

Data Management and Reporting

  • Centralized data collection system via Medidata Rave®
  • 24/7 user support
  • Written data management quality procedures
  • Site training, reporting of data and metrics

Clinical Trials Auditing

  • Independent auditing of trials and processes
  • Guidance to ensure GCP, regulatory, and NCI guidelines are followed
  • Collaboration with Site staff to identify systemic improvements

Administration and Coordination

  • Unified operational structure
  • Procedural documentation
  • Statistical support
  • Biospecimen inventory

Lead Academic Organizations

Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Northwestern Cancer Prevention Consortium
University of Arizona, University of Arizona Cancer Prevention Clinical Trials Network (UA CP-CTNet)
University of Texas MD Anderson Cancer Center, iCAN-PREVENT: International Cancer Prevention Clinical Trial Consortium
University of Michigan, Early Phase Clinical Cancer Prevention Consortium (ClinCaP)
The University of Wisconsin, The MW Chemoprevention Network
Learn more about CP-CTNet on the National Cancer Institute website

This project is supported by the National Cancer Institute (NCI) of the National Institutes of Health under award number U24CA242637. The content is solely the responsibility of the authors and does not necessarily represent the official view of the National Institutes of Health.


Copyright © 2020, Frontier Science and Technology Research Foundation, Inc. All rights reserved.